By W. Hood
The newcomer to the sphere of medical chemistry is confronted with the daunting prospect of realizing the ever expanding facets of the topic: new strategies, checks, terminology, tools of diagnosing illnesses and different advances which relate to scientific chemistry. the purpose of this publication is to supply uncomplicated information about all branches of the topic which the trainee might want to comprehend. The publication also needs to supply a foundation for answering some of the exam questions of scientific chemistry. it really is for this reason was hoping that this ebook will end up precious to anyone beginning a profession in scientific chemistry, be that individual a laboratory clinical officer, graduate or trainee pathologist. at any place attainable, feedback for additional analyzing are given. Many matters are so large notwithstanding that the reader is spoke of the overall checklist of analytical and scientific textbooks provided on the finish of the ebook. My thankful thank you are prolonged to the 3 women who typed this manuscript: Christine Cliffe, Margaret Donnelly and Judith Hardy. i want to thank Dr Brian knowledge of Queens college, Belfast for his feedback at the access "Enzyme-immunoassay". eventually my thank you visit Mr Martin Lister of MTP Press for his support and encouragement during this enterprise. W. H. ASHTON-UNDER-L YNE APRIL 1980 vii A ABETALIPOPROTEINAEMIA a unprecedented hereditary sickness during which there's a whole absence of j3-lipoprotein, pre:f3-1ipoprotein and chylomicrons. It offers clinically as ataxia and malabsorption with steatorrhoea. Thorny formed erythrocytes (acanthocytes) are a function of the disease.
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Additional resources for A–Z of Clinical Chemistry: A Guide for the Trainee
Immunochemistry in Clinical and Laboratory Medicine p. 23 (Lancaster: MTP Press) AUTOMATION The performance of laboratory tests by machines which are capable of carrying out some or all of the procedures which would otherwise have to be carried out manually. Such procedures include pipetting, centrifugation, measurement of optical density (or some other parameter) and calculations. See also: centrifugal analysers, continuous flow analysis, discrete analysis 42 AZOSTIX AZOSTIX A reagent stick manufactured by Ames for the estimation of blood urea.
1, 216 ANALBUMINAEMIA A rare hereditary disease in which there is almost a complete absence of albumin in the serum. The condition is inherited as an autosomal recessive. There appear to be few pathological consequences of the albumin deficiency. Affected individuals often have raised serum globulin levels which may be a compensatory measure to maintain the colloid osmotic pressure. G. D. (1978). Deficiencies of circulating enzymes and plasma proteins. B. S. , p. 1712 (New York: McGraw-Hill) ANDROGENS These are a group of C-19 steroids which influence the male secondary sex characteristics.
Decreases in blood pH or increases in PC02 cause the haemoglobin dissociation curve to move to the right. Alternatively an increase in blood pH or a decrease in PC0 2 cause the curve to move to the left. See also: haemoglobin, P50' BONE A tissue consisting of a collagenous protein matrix impregnated with mineral salts especially hydroxyapatite (a form of calcium phosphate). Cells called osteoblasts are involved in the formation of the collagen fibre network. Also present in bone are cells called osteoclasts which are responsible for bone resorption.